About University of Arizona Cancer Center and Associated Biorepositories

The GI SPORE Biorepository collects and archives tissue and blood biospecimens from routine GI-related surgical procedures. Annotated tumor and non-tumor specimens are present in the Biorepository. Biospecimen requests are reviewed by the GI SPORE Steering Committee. When requesting biospecimens, it is recommended to either design a small feasibility (pilot) study to demonstrate measurement precision, sensitivity and reproducibility or provide such data to support the actual conduct of the proposed project and avert biospecimen loss. The specific aims of the GI SPORE grant and previously approved projects have priority for GI SPORE biospecimens. If the project request is approved, the requestor must obtain and provide a signed copy of the IRB approval (or exception) document, a copy of HIPAA approval (or exception) document and a letter of agreement for the transfer of material(s). ALL unused biospecimen material must be destroyed or returned to the GI SPORE Biorepository. The University of Arizona GI SPORE (P50 CA95060) must be acknowledged in any publications and all reprints must be provided to the GI SPORE Biorepository.

The Skin Biorepository consists of specimens from the Skin Cancer Patient Registry and Tissue Bank (SCPR-TB) and the Skin Cancer Prevention Program Project (SCPPP). The SCPR-TB collects annotated biological specimens from patients with nonmelanoma (NMSC), melanoma, and pre-malignant lesions. The SCPPP contains specimens from prior skin cancer prevention studies. Any study seeking access to tissue or information in the Skin Biorepository must have approval from the UA Institutional Review Board and the respective committees (SCPR-TB or Biospecimen). The specific aims of the SCPPP and previously approved projects have priority for the SCPPP specimens.

The Arizona Lymphoma Repository collects and banks specimens from tissue and blood acquired from patients with hematopoietic malignancies, mainly lymphoma, treated at the University of Arizona Cancer Center. Tumor and non-tumor specimens are present in the repository.

The AZCC Biorepository is managed by TACMASS (Tissue Acquisition and Cellular/Molecular Biology Shared Service), which is responsible for the collection and banking of biospecimens from consented UACC patients who are undergoing surgical procedures at the University of Arizona Medical Center (UAMC). Biospecimens from the following organ systems are currently being banked: gynecologic, breast, prostate, endocrine and lung. The Biospecimen Oversight Committee is responsible for the overall management and utilization of repository material. Preparation of specimens for use by UACC investigators and their collaborators is handled as a routine request through TACMASS, and is charged accordingly.

The Cancer Prevention & Control (CPC) Biorepository collects and archives biospecimens from routine screening colonoscopies and a variety of prevention-related studies. Annotated dysplastic and normal specimens are present in the Biorepository. When requesting biospecimens, it is recommended to either design a small feasibility (pilot) study to demonstrate measurement precision, sensitivity and reproducibility or provide such data to support the actual conduct of the proposed project and avert biospecimen loss. The specific aims of the Colon Cancer Prevention Program Project Grant (CCPP) and previously approved projects have priority for CCPP biospecimens. If the project request is approved, the requestor must obtain and provide a signed copy of the IRB approval (or exception) document, a copy of HIPAA approval (or exception) document and a letter of agreement for the transfer of material(s). ALL unused biospecimen material must be destroyed or returned to the CPC Biorepository. The Colon Cancer Prevention Program Project Grant (NCI/NIH P01 CA41105) must be acknowledged in any publications and all reprints must be provided to the CPC Biorepository.